Vapour Diffusion Sitting Drop Method to Induce Nucleation of Calcium Phosphate on Exfoliated Graphene and Graphene Oxide Flakes

The preparation of graphene/apatite and graphene oxide/apatite hybrid nanocomposites has recently attracted great attention in the biomaterial community. sitting drop vapor diffusion technique been assessed as a preparative method for such this work. employed to induce heterogeneous nucleation growth calcium phosphate presence exfoliated commercial oxide flakes, both labeled with L-Alanine. Exfoliated multilayered flakes were produced by sonication-assisted liquid-phase exfoliation graphite. In composites, apatite nanocrystals displayed similar size shape, but different labile B-type carbonation contributions. Graphene also influenced degree apatite, which was almost half that measured blank, well aggregation state their composites. regard, those composites formed larger aggregates because wider distribution, high-volume percentage nanosheets (of about 4 nm length). Overall, is very useful prepare small amounts nanocomposite high reproducibility.